Weekend Magic in Bolivia
From La Paz Heights to Uyuni's White Desert
Trip Overview
Experience Bolivia's most breathtaking contrasts in just two days, beginning in the world's highest capital city, La Paz, where indigenous culture meets dramatic Andean landscapes. Explore mystical markets, moon-like valleys, and panoramic viewpoints before venturing to the otherworldly Uyuni Salt Flats, one of Earth's most surreal natural wonders. This fast-paced itinerary captures Bolivia's essence through its most iconic attractions, from the vibrant Witches Market to the endless white expanse of the salt desert. You'll witness geological marvels, experience authentic Bolivian culture, and capture photographs that will leave friends speechless. While ambitious, this weekend adventure is perfect for travelers who want maximum impact in minimal time, combining high-altitude urban exploration with remote natural beauty.
Day-by-Day Itinerary
La Paz: Mysticism & Moon Valleys
Where to Stay Tonight
Sopocachi or San Pedro neighborhoods (Mid-range hotel or boutique guesthouse)
These central neighborhoods offer easy access to restaurants, are safer for evening walks, and provide good altitude acclimatization before tomorrow's early departure
Uyuni: The Infinite White Desert
Where to Stay Tonight
Uyuni town center or return to La Paz (Basic hotel in Uyuni or return to La Paz accommodation)
Uyuni offers basic but adequate lodging if staying overnight; alternatively, evening flights return you to La Paz for better hotel options and onward connections
Practical Information
Getting Around
Internal flights are essential for this itinerary - La Paz to Uyuni is a 1-hour flight versus 10+ hours by bus. In La Paz, use radio taxis or ride-sharing apps for safety and convenience. Salt flats tours include 4x4 transportation across the desert. Book all flights in advance as routes can be limited. Consider arriving in La Paz at least one day early to acclimatize to the 3,650-meter altitude before starting this itinerary.
Book Ahead
Book flights between La Paz and Uyuni at least 2 weeks ahead, reserve Uyuni salt flats day tour 1 week minimum, book Alpaca Steps walking tour 2-3 days in advance
Packing Essentials
Layers for temperature extremes, high-altitude sun protection (SPF 50+, sunglasses, wide-brimmed hat), altitude sickness medication, camera with extra batteries (cold drains them quickly), water bottle, warm jacket for evening, comfortable walking shoes
Total Budget
$400-480 for 2 days (excluding international flights and accommodation)
Customize Your Trip
Budget Version
Skip the cultural walking tour and explore La Paz independently using public minibuses. Take an overnight bus to Uyuni instead of flying (adds travel time but saves $120-150). Join a shared group tour for the salt flats with basic lunch included. Stay in hostels in both cities, and eat at local markets. Total savings: approximately $200-250 over the weekend.
Luxury Upgrade
Book a private cultural tour with expert guide in La Paz. Fly both ways to Uyuni with flexible tickets. Arrange a private 4x4 tour of the salt flats with gourmet picnic lunch and champagne sunset. Stay at a salt hotel on the edge of the flats for a unique overnight experience. Dine at La Paz's finest restaurants featuring contemporary Bolivian cuisine. Upgrade to luxury hotels in both locations.
Family-Friendly
The high altitude makes this challenging for young children under 5. For older kids, break up the walking tour into shorter segments with snack breaks. The salt flats are magical for children - bring toys for creative perspective photos. Pack extra snacks and altitude-appropriate activities. Consider spending an extra day in La Paz for better acclimatization. Visit Biocentro Guembe Mariposario if extending your stay for butterfly gardens and pools kids will love.
Book Activities for Your Trip
Tours, tickets, and experiences in Bolivia